Spravato® Therapy for Treatment-Resistant Depression

Spravato® therapy is a groundbreaking, FDA-approved treatment for adults suffering from Treatment-Resistant Depression (TRD) and Major Depressive Disorder (MDD) with suicidal thoughts. It offers hope to those who have not responded to traditional antidepressant medications.

What is Spravato®?

Spravato® (esketamine) is the first FDA-approved nasal spray for Treatment-Resistant Depression. Derived from ketamine, it is more potent, allowing for lower doses and fewer side effects than traditional ketamine treatments.₁ The effects of Spravato® are often felt within the first or second treatment, providing faster relief for patients.

How Does Spravato® Therapy Work?

Spravato® works by targeting the brain's glutamate system, restoring neural connections and improving mood regulation. Administered in-office, patients undergo a two-hour observation period following treatment to monitor any immediate side effects. During this time, patients can relax, listen to music, or use our clinic's free Wi-Fi.

Conditions Treated by Spravato® Therapy

  • Treatment-Resistant Depression (TRD)

  • Major Depressive Disorder (MDD) with suicidal thoughts

Given alongside an oral antidepressant, Spravato® has shown significantly greater symptom reduction compared to placebo treatments within just four weeks.

Is Spravato® Right for You?

Spravato® therapy is ideal for adults diagnosed with TRD or MDD with suicidal ideation who have tried at least two different antidepressants without success. To determine if Spravato® is right for you, schedule a consultation with Dr. David Deichert at SageMED.

Spravato® Treatment Schedule

Patients typically receive Spravato® therapy:

  • Twice a week for the first four weeks

  • Followed by a tapering schedule based on progress

After each session, patients are observed for two hours in the clinic. You will need to arrange for transportation, as you cannot drive post-treatment.

Potential Side Effects of Spravato® Therapy

The majority of side effects occur during the observation period and tend to resolve quickly. These side effects may include:

  • Dissociation

  • Dizziness

  • Nausea

  • Anxiety

  • Fatigue or lethargy

  • Increased blood pressure

  • Vomiting

  • Euphoria

  • Spinning sensation

  • Numbness

Most patients find these side effects mild and manageable.

Frequently Asked Questions (FAQs)

  • Most side effects occur during the two-hour observation window and include dissociation, dizziness, nausea, and mild euphoria. These effects are generally short-lived.

  • Yes, Spravato® is covered by Medicare and most insurance plans. Our team will assist with the prior authorization process. However, after each session, you’ll need to arrange alternative transportation.

  • Many patients begin to feel improvements after their first or second session. Significant symptom relief often occurs within four weeks of starting treatment.

  • Currently, Spravato® is approved for individuals aged 18 and older.

Why Choose SageMED for Spravato® Therapy?

As a trusted integrative health clinic in Bellevue, SageMED provides expert care for patients seeking relief from depression. Our team, led by Dr. David Deichert, offers personalized, compassionate care tailored to your needs.

Schedule Your Spravato® Therapy Consultation Today

If you are struggling with Treatment-Resistant Depression or MDD with suicidal thoughts, contact SageMED today to schedule a consultation and explore how Spravato® therapy can help you regain control of your mental health.

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Schedule an appointment with our Spravato® Therapy specialist today. Our dedicated team is committed to providing expert care to help you manage your joint health effectively. Please use the form below or text us at +1 425-679-6056 to find the best care plan tailored to your needs.

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